A bolus dose of 100 mg is to be infused over 10 minutes. The solution concentration is 25 mg/mL. What is the infusion rate in mL/min?

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Multiple Choice

A bolus dose of 100 mg is to be infused over 10 minutes. The solution concentration is 25 mg/mL. What is the infusion rate in mL/min?

Explanation:
To figure this out, convert the dose to the volume of solution needed using the concentration, then divide by the infusion time to get the rate. You need 100 mg and the solution is 25 mg per mL, so the volume required is 100 ÷ 25 = 4 mL. Infuse that 4 mL over 10 minutes, so the rate is 4 mL ÷ 10 min = 0.4 mL per minute. That rate fits because it exactly delivers 100 mg over 10 minutes. If you used 0.2 mL/min, you’d deliver only 2 mL (50 mg); 0.6 mL/min would be 6 mL (150 mg); 1.0 mL/min would be 10 mL (250 mg).

To figure this out, convert the dose to the volume of solution needed using the concentration, then divide by the infusion time to get the rate.

You need 100 mg and the solution is 25 mg per mL, so the volume required is 100 ÷ 25 = 4 mL. Infuse that 4 mL over 10 minutes, so the rate is 4 mL ÷ 10 min = 0.4 mL per minute.

That rate fits because it exactly delivers 100 mg over 10 minutes. If you used 0.2 mL/min, you’d deliver only 2 mL (50 mg); 0.6 mL/min would be 6 mL (150 mg); 1.0 mL/min would be 10 mL (250 mg).

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